PRE-CONFERENCE SHORT COURSES* | TUESDAY, SEPTEMBER 25 | 2:00 - 5:00 PM
This course will provide an understanding for some of the pharmacological complexities of G protein-coupled receptors (GPCRs) as well as for the tools used to study them in a drug discovery setting. The course is well suited for biologists, pharmacologists
and medicinal chemists who have recently started working with GPCRs or for those who need a refresher on the latest technological advances and newest paradigms.
Instructor: Annette Gilchrist, PhD, Professor, Pharmacology, Midwestern University
Detailed Agenda
PRE-CONFERENCE DINNER SHORT COURSES* | TUESDAY, SEPTEMBER 25 | 6:00 - 8:30 PM
This course aims to educate a diverse group of scientists-chemists, biologists, toxicologists, and those involved in translational and clinical research, about the growing use and applications of AI and ML. Talks start with explaining the basic terminology used and what it means, followed by discussions separating the hope from the hype. It goes into the caveats and limitations in AI and ML, while exploring ways in which it can be successfully applied in the drug discovery and development pipeline. There will be experts from various areas presenting case studies on how they have used AI/ML tools for lead optimization, target discovery, visualizing and classifying large datasets, patient stratification and more.
Instructors: Arvind Rao, PhD, Associate Professor, Department of Computational Medicine and Bioinformatics, University of Michigan
Jin Yao, PhD, Scientific Investigator, Computational Biology and Statistics, Target Sciences, GSK
Nicholas P. Tatonetti, PhD, Herbert Irving Assistant Professor of Biomedical Informatics and Director of Clinical Informatics, Herbert
Irving Comprehensive Cancer Center, Columbia University
Detailed Agenda
DINNER SHORT COURSES* | THURSDAY, SEPTEMBER 27 | 7:00 - 9:30 PM
Our lack of understanding of the molecular basis for compound penetration into and efflux out of gram-negative bacteria has been identified as a key bottleneck for the rational discovery of novel antibacterial compounds. A main driver of this knowledge
gap is the historical lack of assays, tools, and/or predictive models to provide medicinal chemists with structure-activity relationships that could guide optimization of whole cell penetration (and efflux avoidance). However, there have been
some recent, promising advances in the field which set the stage for future innovative approaches.
Instructors: David Six, PhD, Investigator III, Infectious Diseases, Novartis Institutes for BioMedical Research
Ram Iyer, PhD, Principal Scientist (Bacteriology), Entasis Therapeutics, Inc.
Detailed Agenda
See the rest of the short courses here: DiscoveryOnTarget.com/Short-Courses
* Separate registration required